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Poisoning Syndromes
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Toxins
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Characteristics
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Phalloides
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Cyclopeptides - Amatoxins (also Phallotoxins, Virotoxins)
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Latent period usually 8-12 hrs, then severe vomiting and diarrhea, later liver damage.
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Orellanus
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Orellanine (bipyridlyl, similar to Diquat, Paraquat)
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Latent period very long, up to several days, then kidney damage, sometimes GI disturbances.
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Smithiana
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2-amino-4, 5-hexadienoic acid ñ as an amino sugar
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Latent period 4-11 hrs, GI disturbances, renal damage, sometimes liver damage.
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Gyromitra
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Gyromitrin (high instability) (Monomethylhydrazine) [carcinogenic, mutagenic]
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Difficult to distinguish from Phalloides poisoning, often additional central nervous and haemolytic symptoms.
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Muscarine
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Muscarine (alkaloid) [similar to acetylcholine - transmits impulses from synapses of nerve cells to the receptors of muscle, nerve and gland cells]
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Short latent period, GI disturbances, sweating, salvation, lachrymation.
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Pantherina
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Ibotenic Acid, Muscomol (isoxazoles) [stimulates GABA receptors in CN system]
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Short latent period, similar To alcohol intoxication, then deep sleep.
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Psilocybin
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Psilocybin, Psilocin, Baeocystin (indoles) [similar to LSD, structural analogs of serotonin]
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Short latent period, psychotomimetic symptoms predominate, similar to those of LSD intoxication
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Coprinus
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Coprine (prevents further oxidation of acetaldehyde during the metabolism of alcohol - to acetate)
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Requires consumption of alcohol, flushing, reddening of the face, headache, metallic taste in mouth. (Antabuse-like)
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Paxillus
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Immuno-haemolytic anaemia, toxins??
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Short latent period, GI and >haemolytic symptoms, previous history of eating with milder symptoms
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Gastrointentinal
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Various, often unknown
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Short latent period, primarily GI symptoms
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